Detection of Ki-ras mutations in tissue and plasma samples of patients with pancreatic cancer using PNA-mediated PCR clamping and hybridisation probes

In the present study, we combined the PCR-clamping approach with melting curve analysis using mutant specific hybridisation probes and wild-type specific peptide nucleic acids (PNAs) to determine the genotypes of the most frequent point mutation in codon 12 of the proto-oncogene Ki-ras in tissue and...

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Detalles Bibliográficos
Autores principales: Däbritz, J, Hänfler, J, Preston, R, Stieler, J, Oettle, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361834/
https://www.ncbi.nlm.nih.gov/pubmed/15655549
http://dx.doi.org/10.1038/sj.bjc.6602319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361834/
https://www.ncbi.nlm.nih.gov/pubmed/15655549
http://dx.doi.org/10.1038/sj.bjc.6602319

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