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hMSH2 is the most commonly mutated MMR gene in a cohort of Greek HNPCC patients

Germline mutations in genes encoding proteins involved in DNA mismatch repair are responsible for the autosomal dominantly inherited cancer predisposition syndrome hereditary nonpolyposis colorectal cancer (HNPCC). We describe here analysis of hMLH1 and hMSH2 in nine Greek families referred to our c...

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Detalles Bibliográficos
Autores principales:	Apessos, A, Mihalatos, M, Danielidis, I, Kallimanis, G, Agnantis, N J, Triantafillidis, J K, Fountzilas, G, Kosmidis, P A, Razis, E, Georgoulias, V A, Nasioulas, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361846/ https://www.ncbi.nlm.nih.gov/pubmed/15655560 http://dx.doi.org/10.1038/sj.bjc.6602260

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