Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines

MT201 is a fully human monoclonal IgG1 antibody with moderate affinity for epithelial cell adhesion molecule (Ep-CAM) being clinically developed for the treatment of carcinomas. Like many other clinically validated IgG1 monoclonal antibodies, MT201 primarily acts by antibody-dependent cellular cytot...

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Detalles Bibliográficos
Autores principales: Prang, N, Preithner, S, Brischwein, K, Göster, P, Wöppel, A, Müller, J, Steiger, C, Peters, M, Baeuerle, P A, da Silva, A J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361858/
https://www.ncbi.nlm.nih.gov/pubmed/15655555
http://dx.doi.org/10.1038/sj.bjc.6602310

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