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Antitumour activity of XR5944 in vitro and in vivo in combination with 5-fluorouracil and irinotecan in colon cancer cell lines

XR5944 (MLN944), a novel bis-phenazine, has demonstrated potent cytotoxic activity against a variety of murine and human tumour models. In the present study, the antitumour activity of XR5944 was investigated in combination with 5-fluorouracil (5-FU) or irinotecan in human colon carcinoma cell lines...

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Detalles Bibliográficos
Autores principales:	Harris, S M, Mistry, P, Freathy, C, Brown, J L, Charlton, P A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361868/ https://www.ncbi.nlm.nih.gov/pubmed/15700035 http://dx.doi.org/10.1038/sj.bjc.6602403

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