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Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis
The death ligand TRAIL (Apo2L) has potential for cancer therapy, since tumour cells are thought to be more sensitive than normal cells. We investigated whether sensitivity to TRAIL increases during the adenoma to carcinoma transition of colorectal carcinogenesis. Under the same culture conditions, w...
Autores principales: | Hague, A, Hicks, D J, Hasan, F, Smartt, H, Cohen, G M, Paraskeva, C, MacFarlane, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361885/ https://www.ncbi.nlm.nih.gov/pubmed/15685228 http://dx.doi.org/10.1038/sj.bjc.6602387 |
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