High viral loads of human papillomavirus predict risk of invasive cervical carcinoma

High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9–151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5–7.2)...

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Detalles Bibliográficos
Autores principales: Moberg, M, Gustavsson, I, Wilander, E, Gyllensten, U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361906/
https://www.ncbi.nlm.nih.gov/pubmed/15756259
http://dx.doi.org/10.1038/sj.bjc.6602436
Descripción
Sumario:High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9–151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5–7.2). Thus, HPV load is a type-dependent risk marker for invasive carcinoma.

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