High viral loads of human papillomavirus predict risk of invasive cervical carcinoma

High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9–151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5–7.2)...

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Autores principales: Moberg, M, Gustavsson, I, Wilander, E, Gyllensten, U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361906/
https://www.ncbi.nlm.nih.gov/pubmed/15756259
http://dx.doi.org/10.1038/sj.bjc.6602436
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author Moberg, M
Gustavsson, I
Wilander, E
Gyllensten, U
author_facet Moberg, M
Gustavsson, I
Wilander, E
Gyllensten, U
author_sort Moberg, M
collection PubMed
description High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9–151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5–7.2). Thus, HPV load is a type-dependent risk marker for invasive carcinoma.
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spelling pubmed-23619062009-09-10 High viral loads of human papillomavirus predict risk of invasive cervical carcinoma Moberg, M Gustavsson, I Wilander, E Gyllensten, U Br J Cancer Molecular Diagnostics High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9–151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5–7.2). Thus, HPV load is a type-dependent risk marker for invasive carcinoma. Nature Publishing Group 2005-03-14 2005-03-01 /pmc/articles/PMC2361906/ /pubmed/15756259 http://dx.doi.org/10.1038/sj.bjc.6602436 Text en Copyright © 2005 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Molecular Diagnostics
Moberg, M
Gustavsson, I
Wilander, E
Gyllensten, U
High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
title High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
title_full High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
title_fullStr High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
title_full_unstemmed High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
title_short High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
title_sort high viral loads of human papillomavirus predict risk of invasive cervical carcinoma
topic Molecular Diagnostics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361906/
https://www.ncbi.nlm.nih.gov/pubmed/15756259
http://dx.doi.org/10.1038/sj.bjc.6602436
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