Aberrant methylation of SPARC in human lung cancers

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SPARC (secreted protein acidic and rich in cysteine) is an extracellular Ca(2+)-binding matricellular glycoprotein associated with the regulation of cell adhesion and growth. We investigated loss of expression of SPARC gene and promoter methylation in lung cancers and correlated the data with clinic...

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Detalles Bibliográficos
Autores principales: Suzuki, M, Hao, C, Takahashi, T, Shigematsu, H, Shivapurkar, N, Sathyanarayana, U G, Iizasa, T, Fujisawa, T, Hiroshima, K, Gazdar, A F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361924/
https://www.ncbi.nlm.nih.gov/pubmed/15756262
http://dx.doi.org/10.1038/sj.bjc.6602376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361924/
https://www.ncbi.nlm.nih.gov/pubmed/15756262
http://dx.doi.org/10.1038/sj.bjc.6602376

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