Cargando…

Efficacy of epidermal growth factor receptor-targeted molecular therapy in anaplastic thyroid cancer cell lines

Anaplastic thyroid cancer is one of the most aggressive human malignancies and the outcomes of conventional therapy have been far from satisfactory. Recently, epidermal growth factor receptor (EGFR)-targeted therapy has been introduced as an alternative therapeutic strategy for highly malignant canc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nobuhara, Y, Onoda, N, Yamashita, Y, Yamasaki, M, Ogisawa, K, Takashima, T, Ishikawa, T, Hirakawa, K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361935/ https://www.ncbi.nlm.nih.gov/pubmed/15785737 http://dx.doi.org/10.1038/sj.bjc.6602461

Ejemplares similares

Poorly differentiated and anaplastic thyroid carcinomas: chromosomal and oligo-array profile of five new cell lines
por: Rodrigues, R F, et al.
Publicado: (2007)

BRAF(V600E) mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas
por: Takano, T, et al.
Publicado: (2007)

Decreased expression of haemoglobin beta (HBB) gene in anaplastic thyroid cancer and recovory of its expression inhibits cell growth
por: Onda, M, et al.
Publicado: (2005)

UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas
por: Pallante, P, et al.
Publicado: (2005)

Significance of E-cadherin expression in triple-negative breast cancer
por: Kashiwagi, S, et al.
Publicado: (2010)

Clinical significance of heparin-binding epidermal growth factor-like growth factor in peritoneal fluid of ovarian cancer
por: Yagi, H, et al.
Publicado: (2005)

Reduction of PTEN protein and loss of epidermal growth factor receptor gene mutation in lung cancer with natural resistance to gefitinib (IRESSA)
por: Kokubo, Y, et al.
Publicado: (2005)

Impacts of excision repair cross-complementing gene 1 (ERCC1), dihydropyrimidine dehydrogenase, and epidermal growth factor receptor on the outcomes of patients with advanced gastric cancer
por: Matsubara, J, et al.
Publicado: (2008)

Peroxisome Proliferator‐activated Receptor Gamma Activation Induces Cell Cycle Arrest via the p53‐independent Pathway in Human Anaplastic Thyroid Cancer Cells
por: Chung, Sung Hwa, et al.
Publicado: (2002)

Differential radiosensitisation by ZD1839 (Iressa), a highly selective epidermal growth factor receptor tyrosine kinase inhibitor in two related bladder cancer cell lines
por: Maddineni, S B, et al.
Publicado: (2005)

Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma
por: Kato, Y, et al.
Publicado: (2010)

Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer
por: Takahashi, N, et al.
Publicado: (2014)

Epidermal growth factor receptor gene copy number aberration at the primary tumour is significantly associated with extracapsular spread in oral cancer
por: Michikawa, C, et al.
Publicado: (2011)

Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA)
por: Kimura, H, et al.
Publicado: (2007)

Mutations in Rb1 pathway-related genes are associated with poor prognosis in Anaplastic Astrocytomas
por: Bäcklund, L M, et al.
Publicado: (2005)

Differential miRNA expression profiles in variants of papillary thyroid carcinoma and encapsulated follicular thyroid tumours
por: Sheu, S-Y, et al.
Publicado: (2010)

Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa
por: Piazzi, G, et al.
Publicado: (2006)

Regulation of anoikis resistance by NADPH oxidase 4 and epidermal growth factor receptor
por: Kim, Hyeryeong, et al.
Publicado: (2017)

Alteration of the serum levels of the epidermal growth factor receptor and its ligands in patients with non-small cell lung cancer and head and neck carcinoma
por: Lemos-González, Y, et al.
Publicado: (2007)

Mutations in the epidermal growth factor receptor gene are linked to smoking-independent, lung adenocarcinoma
por: Sonobe, M, et al.
Publicado: (2005)

Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor status
por: Hofman, P, et al.
Publicado: (2008)

PI3K/Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma
por: Matsuoka, T, et al.
Publicado: (2012)

Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia
por: Nankivell, P, et al.
Publicado: (2013)

Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells
por: Fuyuhiro, Y, et al.
Publicado: (2011)

Identification of the high-risk group for metastasis of gastric cancer cases by vascular endothelial growth factor receptor-1 overexpression in peripheral blood
por: Kosaka, Y, et al.
Publicado: (2007)

Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients
por: Scartozzi, M, et al.
Publicado: (2011)

Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression
por: Ko, Young San, et al.
Publicado: (2015)

Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer
por: Murata, A, et al.
Publicado: (2013)

Direct cancer–stromal interaction increases fibroblast proliferation and enhances invasive properties of scirrhous-type gastric carcinoma cells
por: Semba, S, et al.
Publicado: (2009)

Comprehensive epidermal growth factor receptor gene analysis from cytological specimens of non-small-cell lung cancers
por: Savic, S, et al.
Publicado: (2008)

Monitoring gastric cancer progression with circulating tumour DNA
por: Hamakawa, T, et al.
Publicado: (2015)

High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer
por: Hamano, R, et al.
Publicado: (2012)

Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib
por: Lemos, C, et al.
Publicado: (2009)

Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma
por: Yamasaki, M, et al.
Publicado: (2011)

Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma
por: Lee, S, et al.
Publicado: (2010)

SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis
por: Otsubo, T, et al.
Publicado: (2008)

Genetic instability in lung cancer: concurrent analysis of chromosomal, mini- and microsatellite instability and loss of heterozygosity
por: Ninomiya, H, et al.
Publicado: (2006)

Expression of uPAR mRNA in peripheral blood is a favourite marker for metastasis in gastric cancer cases
por: Kita, Y, et al.
Publicado: (2009)

CD26 expression on T cell lines increases SDF-1-α-mediated invasion
por: Havre, P A, et al.
Publicado: (2009)

Clinical implications of insulin-like growth factor 1 system in early-stage cervical cancer
por: Huang, Y-F, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_gh1d7ov9pm8s7ljm3tkbjtj9bk