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Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liver

The largest single underlying cause of hepatocellular carcinoma (HCC) worldwide is hepatitis B virus (HBV) infection. Hepatitis B virus increases cellular oxidative stress and the development of HCC occurs after a long latency period. The study was carried out to determine whether mitochondrial DNA...

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Detalles Bibliográficos
Autores principales: Wheelhouse, N M, Lai, P B S, Wigmore, S J, Ross, J A, Harrison, D J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361973/
https://www.ncbi.nlm.nih.gov/pubmed/15785740
http://dx.doi.org/10.1038/sj.bjc.6602496