Lack of clinical efficacy of imatinib in metastatic melanoma

This two-centre phase-II trial aimed at investigating the efficacy of imatinib in metastasised melanoma patients in correlation to the tumour expression profile of the imatinib targets c-kit and platelet-derived growth factor receptor (PDGF-R). The primary study end point was objective response acco...

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Detalles Bibliográficos
Autores principales: Ugurel, S, Hildenbrand, R, Zimpfer, A, La Rosée, P, Paschka, P, Sucker, A, Keikavoussi, P, Becker, J C, Rittgen, W, Hochhaus, A, Schadendorf, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362005/
https://www.ncbi.nlm.nih.gov/pubmed/15846297
http://dx.doi.org/10.1038/sj.bjc.6602529

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