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The development and characterisation of porphyrin isothiocyanate–monoclonal antibody conjugates for photoimmunotherapy
A promising approach to increase the specificity of photosensitisers used in photodynamic therapy has been through conjugation to monoclonal antibodies (MAb) directed against tumour-associated antigens. Many of the conjugations performed to date have relied on the activated ester method, which can l...
Autores principales: | Hudson, R, Carcenac, M, Smith, K, Madden, L, Clarke, O J, Pèlegrin, A, Greenman, J, Boyle, R W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362018/ https://www.ncbi.nlm.nih.gov/pubmed/15812551 http://dx.doi.org/10.1038/sj.bjc.6602517 |
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