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Selective inhibition of TNF-α-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib

We have reported that the selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, gefitinib (‘Iressa’, ZD1839), suppressed intrahepatic metastasis of hepatocellular carcinoma CBO140C12 cells. In this study, we focused on the tumour necrosis factor-α (TNF-α) signalling pathways....

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Detalles Bibliográficos
Autores principales:	Ueno, Y, Sakurai, H, Matsuo, M, Choo, M K, Koizumi, K, Saiki, I
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362047/ https://www.ncbi.nlm.nih.gov/pubmed/15841081 http://dx.doi.org/10.1038/sj.bjc.6602548

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