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Effects of cisplatin on olfactory function in cancer patients

A prospective analysis of olfaction was performed in 21 patients receiving cisplatin. A reduction in olfactory function was noted in only one patient. Hearing impairment was documented in nine patients, none of whom had impaired sense of smell. We conclude that cisplatin has no major deleterious eff...

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Detalles Bibliográficos
Autores principales: Yakirevitch, A, Talmi, Y P, Baram, Y, Weitzen, R, Pfeffer, M R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362049/
https://www.ncbi.nlm.nih.gov/pubmed/15827551
http://dx.doi.org/10.1038/sj.bjc.6602544
Descripción
Sumario:A prospective analysis of olfaction was performed in 21 patients receiving cisplatin. A reduction in olfactory function was noted in only one patient. Hearing impairment was documented in nine patients, none of whom had impaired sense of smell. We conclude that cisplatin has no major deleterious effect on olfactory function at doses which cause hearing impairment.