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A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)
There is considerable evidence that human genetic variation influences gene expression. Genome-wide studies have revealed that mRNA levels are associated with genetic variation in or close to the gene coding for those mRNA transcripts – cis effects, and elsewhere in the genome – trans effects. The r...
Autores principales: | Melzer, David, Perry, John R. B., Hernandez, Dena, Corsi, Anna-Maria, Stevens, Kara, Rafferty, Ian, Lauretani, Fulvio, Murray, Anna, Gibbs, J. Raphael, Paolisso, Giuseppe, Rafiq, Sajjad, Simon-Sanchez, Javier, Lango, Hana, Scholz, Sonja, Weedon, Michael N., Arepalli, Sampath, Rice, Neil, Washecka, Nicole, Hurst, Alison, Britton, Angela, Henley, William, van de Leemput, Joyce, Li, Rongling, Newman, Anne B., Tranah, Greg, Harris, Tamara, Panicker, Vijay, Dayan, Colin, Bennett, Amanda, McCarthy, Mark I., Ruokonen, Aimo, Jarvelin, Marjo-Riitta, Guralnik, Jack, Bandinelli, Stefania, Frayling, Timothy M., Singleton, Andrew, Ferrucci, Luigi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362067/ https://www.ncbi.nlm.nih.gov/pubmed/18464913 http://dx.doi.org/10.1371/journal.pgen.1000072 |
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