Use of antibiotics and risk of breast cancer: a population-based case–control study

We examined the use of antibiotics among 2728 women with a first diagnosis of breast cancer during 1994–2003, and 27 280 population controls in North Jutland County, Denmark, based on hospital discharge diagnoses, prescription use from 1989 to 2002, and population registry data. We found no increase...

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Autores principales: Sørensen, H T, Skriver, M V, Friis, S, McLaughlin, J K, Blot, W J, Baron, J A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362073/
https://www.ncbi.nlm.nih.gov/pubmed/15611791
http://dx.doi.org/10.1038/sj.bjc.6602313
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author Sørensen, H T
Skriver, M V
Friis, S
McLaughlin, J K
Blot, W J
Baron, J A
author_facet Sørensen, H T
Skriver, M V
Friis, S
McLaughlin, J K
Blot, W J
Baron, J A
author_sort Sørensen, H T
collection PubMed
description We examined the use of antibiotics among 2728 women with a first diagnosis of breast cancer during 1994–2003, and 27 280 population controls in North Jutland County, Denmark, based on hospital discharge diagnoses, prescription use from 1989 to 2002, and population registry data. We found no increased relative risk of breast cancer associated with use compared with nonuse. The odds ratio for breast cancer associated with more than 10 prescriptions for antibiotics was 1.00 (95% CI 0.86 –1.15). Relative risks were similar for different classes of antibiotics. A subanalysis based on cases and controls younger than 70 years of age, with data on first birth and number of children, showed similar risk estimates even after adjustment for age at first birth and parity. In our study, use of antibiotics was not associated with an increased risk of breast cancer.
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spelling pubmed-23620732009-09-10 Use of antibiotics and risk of breast cancer: a population-based case–control study Sørensen, H T Skriver, M V Friis, S McLaughlin, J K Blot, W J Baron, J A Br J Cancer Epidemiology We examined the use of antibiotics among 2728 women with a first diagnosis of breast cancer during 1994–2003, and 27 280 population controls in North Jutland County, Denmark, based on hospital discharge diagnoses, prescription use from 1989 to 2002, and population registry data. We found no increased relative risk of breast cancer associated with use compared with nonuse. The odds ratio for breast cancer associated with more than 10 prescriptions for antibiotics was 1.00 (95% CI 0.86 –1.15). Relative risks were similar for different classes of antibiotics. A subanalysis based on cases and controls younger than 70 years of age, with data on first birth and number of children, showed similar risk estimates even after adjustment for age at first birth and parity. In our study, use of antibiotics was not associated with an increased risk of breast cancer. Nature Publishing Group 2005-02-14 2004-12-21 /pmc/articles/PMC2362073/ /pubmed/15611791 http://dx.doi.org/10.1038/sj.bjc.6602313 Text en Copyright © 2005 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Sørensen, H T
Skriver, M V
Friis, S
McLaughlin, J K
Blot, W J
Baron, J A
Use of antibiotics and risk of breast cancer: a population-based case–control study
title Use of antibiotics and risk of breast cancer: a population-based case–control study
title_full Use of antibiotics and risk of breast cancer: a population-based case–control study
title_fullStr Use of antibiotics and risk of breast cancer: a population-based case–control study
title_full_unstemmed Use of antibiotics and risk of breast cancer: a population-based case–control study
title_short Use of antibiotics and risk of breast cancer: a population-based case–control study
title_sort use of antibiotics and risk of breast cancer: a population-based case–control study
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362073/
https://www.ncbi.nlm.nih.gov/pubmed/15611791
http://dx.doi.org/10.1038/sj.bjc.6602313
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