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Expression of V(1A) and GRP receptors leads to cellular transformation and increased sensitivity to substance-P analogue-induced growth inhibition

Small-cell lung cancer (SCLC) is a particularly aggressive cancer, which metastasises early. Despite initial sensitivity to radio- and chemo-therapy, it invariably relapses, so that the 2-year survival remains less than 5%. Neuropeptides particularly arginine vasopressin (AVP) and gastrin-releasing...

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Detalles Bibliográficos
Autores principales:	MacKinnon, A C, Tufail-Hanif, U, Lucas, C D, Jodrell, D, Haslett, C, Sethi, T
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2005
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362091/ https://www.ncbi.nlm.nih.gov/pubmed/15685238 http://dx.doi.org/10.1038/sj.bjc.6602366

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