Tamoxifen induces oxidative stress and apoptosis in oestrogen receptor-negative human cancer cell lines

Recent data have demonstrated that the anti-oestrogen tamoxifen (TAM) is able to facilitate apoptosis in cancer cells not expressing oestrogen receptor (ER). In an attempt to identify the biochemical pathway for this phenomenon, we investigated the role of TAM as an oxidative stress agent. In two ER...

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Detalles Bibliográficos
Autores principales: Ferlini, C, Scambia, G, Marone, M, Distefano, M, Gaggini, C, Ferrandina, G, Fattorossi, A, Isola, G, Panici, P Benedetti, Mancuso, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362195/
https://www.ncbi.nlm.nih.gov/pubmed/9888466
http://dx.doi.org/10.1038/sj.bjc.6690042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362195/
https://www.ncbi.nlm.nih.gov/pubmed/9888466
http://dx.doi.org/10.1038/sj.bjc.6690042

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