Selective inhibition of MDR1 P-glycoprotein-mediated transport by the acridone carboxamide derivative GG918

The acridone carboxamide derivative GG918 (N-{4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)-ethyl]-phenyl}-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide) is a potent inhibitor of MDR1 P-glycoprotein-mediated multidrug resistance. Direct measurements of ATP-dependent MDR1 P-glycoprote...

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Detalles Bibliográficos
Autores principales: Wallstab, A, Koester, M, Böhme, M, Keppler, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362229/
https://www.ncbi.nlm.nih.gov/pubmed/10098736
http://dx.doi.org/10.1038/sj.bjc.6690169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362229/
https://www.ncbi.nlm.nih.gov/pubmed/10098736
http://dx.doi.org/10.1038/sj.bjc.6690169

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