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Delivery of methoxymorpholinyl doxorubicin by interleukin 2-activated NK cells: effect in mice bearing hepatic metastases

The possibility of using interleukin 2 (IL-2)-activated natural killer cells (A-NK) to carry methoxymorpholinyl doxorubicin (MMDX; PNU 152243) to liver-infiltrating tumours was explored in mice bearing 2-day established M5076 reticulum cell sarcoma hepatic metastases. In vitro, MMDX was 5.5-fold mor...

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Detalles Bibliográficos
Autores principales: Quintieri, L, Rosato, A, Amboldi, N, Vizler, C, Ballinari, D, Zanovello, P, Collavo, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362260/
https://www.ncbi.nlm.nih.gov/pubmed/10098738
http://dx.doi.org/10.1038/sj.bjc.6690171