Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas

Since proteolysis of the dermal collagenous matrix and basement membranes is required for local invasive growth and early metastasis formation of cutaneous melanomas, we have analysed the activities/expression levels of certain metalloproteinases in melanomas and cultured melanoma cells by in situ h...

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Detalles Bibliográficos
Autores principales: Airola, K, Karonen, T, Vaalamo, M, Lehti, K, Lohi, J, Kariniemi, A-L, Keski-Oja, J, Saarialho-Kere, U K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362286/
https://www.ncbi.nlm.nih.gov/pubmed/10360651
http://dx.doi.org/10.1038/sj.bjc.6690417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362286/
https://www.ncbi.nlm.nih.gov/pubmed/10360651
http://dx.doi.org/10.1038/sj.bjc.6690417

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