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Somatic mutation of PTEN in bladder carcinoma

The tumour suppressor gene PTEN/MMAC1, which is mutated or homozygously deleted in glioma, breast and prostate cancer, is mapped to a region of 10q which shows loss of heterozygosity (LOH) in bladder cancer. We screened 123 bladder tumours for LOH in the region of PTEN. In 53 informative muscle inva...

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Detalles Bibliográficos
Autores principales:	Aveyard, J S, Skilleter, A, Habuchi, T, Knowles, M A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362287/ https://www.ncbi.nlm.nih.gov/pubmed/10360673 http://dx.doi.org/10.1038/sj.bjc.6690439

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