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MMP-2 release and activation in ovarian carcinoma: the role of fibroblasts

The matrix metalloproteinase MMP-2 is up-regulated in epithelial cancers and its mRNA localizes to stromal fibroblasts. In this paper we show that co-culture of ovarian carcinoma cells with fibroblasts resulted in an enhanced release of proMMP-2 and TIMP-2 into the culture medium. Cell–cell interact...

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Detalles Bibliográficos
Autores principales:	Boyd, R S, Balkwill, F R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362343/ https://www.ncbi.nlm.nih.gov/pubmed/10408832 http://dx.doi.org/10.1038/sj.bjc.6690357

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