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Cytotoxic response of ovarian cancer cell lines to IFN-γ is associated with sustained induction of IRF-1 and p21 mRNA

Intereferon-γ (IFN-γ) has some anti-tumour activity in human ovarian cancer. This cytokine inhibited proliferation in three of four ovarian cancer cell lines in vitro. We then compared the action of IFN-γ in two cell lines, one sensitive and one resistant to its growth inhibitory effects. IFN-γ sign...

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Detalles Bibliográficos
Autores principales:	Burke, F, Smith, P D, Crompton, M R, Upton, C, Balkwill, F R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362378/ https://www.ncbi.nlm.nih.gov/pubmed/10376977 http://dx.doi.org/10.1038/sj.bjc.6690491

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