Cargando…

Suppression of telomerase reverse transcriptase (hTERT) expression in differentiated HL-60 cells: regulatory mechanisms

Telomerase activity, associated with cellular immortalization and tumorigenesis, is suppressed during terminal differentiation of HL-60 promyelocytic leukaemic cells. However, it is poorly understood how telomerase activity is regulated in differentiated HL-60 cells. In the present study, we demonst...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, D, Gruber, A, Björkholm, M, Peterson, C, Pisa, P
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362380/ https://www.ncbi.nlm.nih.gov/pubmed/10376966 http://dx.doi.org/10.1038/sj.bjc.6690480

Ejemplares similares

Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
por: Lantuejoul, S, et al.
Publicado: (2004)

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene
por: Ramlee, Muhammad Khairul, et al.
Publicado: (2016)

Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer
por: Yang, Ruozhu, et al.
Publicado: (2023)

Lysine-Specific Demethylase 1 (LSD1) Is Required for the Transcriptional Repression of the Telomerase Reverse Transcriptase (hTERT) Gene
por: Zhu, Qingjun, et al.
Publicado: (2008)

Human Telomerase Reverse Transcriptase (hTERT) Q169 Is Essential for Telomerase Function In Vitro and In Vivo
por: Wyatt, Haley D. M., et al.
Publicado: (2009)

Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer
por: Leão, Ricardo, et al.
Publicado: (2018)

Mechanism of Human Telomerase Reverse Transcriptase (hTERT) Regulation and Clinical Impacts in Leukemia
por: Yik, Mot Yee, et al.
Publicado: (2021)

Naïve T-cells in Myelodysplastic Syndrome Display Intrinsic Human Telomerase Reverse Transcriptase (hTERT) Deficiency
por: Yang, Lili, et al.
Publicado: (2012)

Alternative Splicing of Human Telomerase Reverse Transcriptase (hTERT) and Its Implications in Physiological and Pathological Processes
por: Plyasova, Anna A., et al.
Publicado: (2021)

Research Progress on G-Quadruplexes in Human Telomeres and Human Telomerase Reverse Transcriptase (hTERT) Promoter
por: Gu, Wei, et al.
Publicado: (2022)

Copy-number-gain of telomerase reverse transcriptase (hTERT) is associated with an unfavorable prognosis in esophageal adenocarcinoma
por: Lyu, Su Ir, et al.
Publicado: (2023)

HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT)
por: Kuhlmann, Anne-Sophie, et al.
Publicado: (2007)

Proteomic identification of proteins differentially expressed following overexpression of hTERT (human telomerase reverse transcriptase) in cancer cells
por: Jaiswal, Rishi Kumar, et al.
Publicado: (2017)

mRNA quantification and clinical evaluation of telomerase reverse transcriptase subunit (hTERT) in intracranial tumours of patients in the island of Crete
por: Yannopoulos, A, et al.
Publicado: (2005)

Expression Pattern of Telomerase Reverse Transcriptase (hTERT) Variants and Bcl-2 in Peripheral Lymphocytes of Systemic Lupus Erythematosus Patients
por: Attar, Armin, et al.
Publicado: (2020)

Expression Pattern of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase (hTERT) in Cancer Cell Lines Was not Associated with the Origin of the Cells
por: Khosravi- Maharlooei, Mohsen, et al.
Publicado: (2015)

Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression
por: Tang, Bo, et al.
Publicado: (2015)

Transcriptional Regulation of Telomerase Reverse Transcriptase (TERT) by MYC
por: Khattar, Ekta, et al.
Publicado: (2017)

In silico Analysis of Human Telomerase Reverse Transcriptase (hTERT) Gene: Identification of a Distant Homolog of Melanoma Antigen Family Gene (MAGE)
por: Amin, Ruhul, et al.
Publicado: (2009)

Ablation of human telomerase reverse transcriptase (hTERT) induces cellular senescence in gastric cancer through a galectin-3 dependent mechanism
por: La, Sun-Hyuk, et al.
Publicado: (2016)

Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics
por: Yuan, Xiaotian, et al.
Publicado: (2019)

Interferon-Inducible IFI16, a Negative Regulator of Cell Growth, Down-Regulates Expression of Human Telomerase Reverse Transcriptase (hTERT) Gene
por: Song, Lynda Li, et al.
Publicado: (2010)

Polymorphisms in human telomerase reverse transcriptase (hTERT) gene, gene- gene and gene-smoking interaction with susceptibility to gastric cancer in Chinese Han population
por: Zhang, Jian, et al.
Publicado: (2017)

Expression of telomerase-associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinoma
por: Toshikuni, N, et al.
Publicado: (2000)

Expression of Telomerase Reverse Transcriptase in Psoriatic Lesional Skin
por: Mahmoud, Moushira A., et al.
Publicado: (2006)

The correlations between DNA methylation and polymorphisms in the promoter region of the human telomerase reverse transcriptase (hTERT) gene with postoperative recurrence in patients with thyroid carcinoma (TC)
por: Li, Jian-Jun, et al.
Publicado: (2017)

Evaluation of Energy Balance on Human Telomerase Reverse Transcriptase (hTERT) Alternative Splicing by Semi-quantitative RT-PCR in Human Umbilical Vein Endothelial Cells
por: Behjati, Mohaddeseh, et al.
Publicado: (2017)

Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review
por: McKelvey, Brittany A., et al.
Publicado: (2020)

hTERT promotes cell adhesion and migration independent of telomerase activity
por: Liu, Haiying, et al.
Publicado: (2016)

PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity
por: Zhou, Li-Na, et al.
Publicado: (2015)

The role of telomerase reverse transcriptase (TERT) promoter mutations in prognosis in bladder cancer
por: Wan, Song, et al.
Publicado: (2021)

Reactivation of telomerase reverse transcriptase expression in cancer: the role of TERT promoter mutations
por: Tornesello, Maria Lina, et al.
Publicado: (2023)

Inhibition of Human Telomerase Reverse Transcritpase (hTERT) and Telomerase Activity by Curcumin in Human Mammary Epithelial and Breast Carcinoma Cell Lines
por: Ramachandran, Chappail, et al.
Publicado: (2001)

Diverse regulatory manners of human telomerase reverse transcriptase
por: Jie, Meng-Meng, et al.
Publicado: (2019)

Effects of hTERT transfection on the telomere and telomerase of Periplaneta americana cells in vitro
por: Ma, Chenjing, et al.
Publicado: (2023)

Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues
por: Sæbøe-Larssen, Stein, et al.
Publicado: (2006)

Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications
por: Liu, Tiantian, et al.
Publicado: (2016)

Exploring the epigenetic regulation of telomerase reverse transcriptase (TERT) in human cancer cell lines
por: McKelvey, Brittany A., et al.
Publicado: (2020)

An Identification and Characterization of the Axolotl (Ambystoma mexicanum, Amex) Telomerase Reverse Transcriptase (Amex TERT)
por: Springhetti, Sina, et al.
Publicado: (2022)

Cell membrane breakage and triggering T cell infiltration are involved in human telomerase reverse transcriptase (hTERT) promoter-driven novel peptide KK-64 for liver cancer gene therapy
por: Lu, Yuanhua, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dg32vh7imfcsik38g3aq0smllm