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Loss of heterozygosity (LOH), malignancy grade and clonality in microdissected prostate cancer

The aim of the present study was to find out whether increasing malignancy of prostate carcinoma correlates with an overall increase of loss of heterozygosity (LOH), and whether LOH typing of microdissected tumour areas can help to distinguish between multifocal or clonal tumour development. In 47 c...

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Detalles Bibliográficos
Autores principales: Hügel, A, Wernert, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362403/
https://www.ncbi.nlm.nih.gov/pubmed/10027329
http://dx.doi.org/10.1038/sj.bjc.6690087

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