Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients

18-Fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) has previously been used successfully to image primary and metastatic breast cancer. In this pilot study, 19 breast cancer patients with symptoms/signs referrable to the brachial plexus were evaluated with (18)FDG-PET. In 11 cases com...

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Autores principales: Ahmad, A, Barrington, S, Maisey, M, Rubens, R D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362404/
https://www.ncbi.nlm.nih.gov/pubmed/10027316
http://dx.doi.org/10.1038/sj.bjc.6690074
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author Ahmad, A
Barrington, S
Maisey, M
Rubens, R D
author_facet Ahmad, A
Barrington, S
Maisey, M
Rubens, R D
author_sort Ahmad, A
collection PubMed
description 18-Fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) has previously been used successfully to image primary and metastatic breast cancer. In this pilot study, 19 breast cancer patients with symptoms/signs referrable to the brachial plexus were evaluated with (18)FDG-PET. In 11 cases computerized tomography (CT) scanning was also performed. Of the 19 patients referred for PET study, 14 had abnormal uptake of (18)FDG in the region of the symptomatic plexus. Four patients had normal PET studies and one had increased FDG uptake in the chest wall that accounted for her axillary pain. CT scans were performed in 9 of the 14 patients who had positive brachial plexus PET studies; six of these were either normal or showed no clear evidence of recurrent disease, while three CTs demonstrated clear brachial plexus involvement. Of two of the four patients with normal PET studies, one has had complete resolution of symptoms untreated while the other was found to have cervical disc herniation on magnetic resonance imaging (MRI) scan. The remaining two patients almost certainly had radiation-induced plexopathy and had normal CT, MRI and PET study. These data suggest that (18)FDG-PET scanning is a useful tool in evaluation of patients with suspected metastatic plexopathy, particularly if other imaging studies are normal. It may also be useful in distinguishing between radiation-induced and metastatic plexopathy. © 1999 Cancer Research Campaign
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spelling pubmed-23624042009-09-10 Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients Ahmad, A Barrington, S Maisey, M Rubens, R D Br J Cancer Regular Article 18-Fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) has previously been used successfully to image primary and metastatic breast cancer. In this pilot study, 19 breast cancer patients with symptoms/signs referrable to the brachial plexus were evaluated with (18)FDG-PET. In 11 cases computerized tomography (CT) scanning was also performed. Of the 19 patients referred for PET study, 14 had abnormal uptake of (18)FDG in the region of the symptomatic plexus. Four patients had normal PET studies and one had increased FDG uptake in the chest wall that accounted for her axillary pain. CT scans were performed in 9 of the 14 patients who had positive brachial plexus PET studies; six of these were either normal or showed no clear evidence of recurrent disease, while three CTs demonstrated clear brachial plexus involvement. Of two of the four patients with normal PET studies, one has had complete resolution of symptoms untreated while the other was found to have cervical disc herniation on magnetic resonance imaging (MRI) scan. The remaining two patients almost certainly had radiation-induced plexopathy and had normal CT, MRI and PET study. These data suggest that (18)FDG-PET scanning is a useful tool in evaluation of patients with suspected metastatic plexopathy, particularly if other imaging studies are normal. It may also be useful in distinguishing between radiation-induced and metastatic plexopathy. © 1999 Cancer Research Campaign Nature Publishing Group 1999-02 /pmc/articles/PMC2362404/ /pubmed/10027316 http://dx.doi.org/10.1038/sj.bjc.6690074 Text en Copyright © 1999 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Ahmad, A
Barrington, S
Maisey, M
Rubens, R D
Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients
title Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients
title_full Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients
title_fullStr Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients
title_full_unstemmed Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients
title_short Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients
title_sort use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362404/
https://www.ncbi.nlm.nih.gov/pubmed/10027316
http://dx.doi.org/10.1038/sj.bjc.6690074
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