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Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc
Apoptosis plays a major role in gastrointestinal epithelial cell turnover, ulcerogenesis and tumorigenesis. We have examined apoptosis induction by non-steroidal anti-inflammatory drugs (NSAIDs) in human gastric (AGS) cancer cells and the role of protein kinase C (PKC) and apoptosis-related oncogene...
Autores principales: | Zhu, G H, Wong, B C Y, Eggo, M C, Ching, C K, Yuen, S T, Chan, E Y T, Lai, K C, Lam, S K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362449/ https://www.ncbi.nlm.nih.gov/pubmed/10027304 http://dx.doi.org/10.1038/sj.bjc.6690062 |
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