High efficiency of benzoporphyrin derivative in the photodynamic therapy of pigmented malignant melanoma

Benzoporphyrin derivative monoacid ring A (verteporfin, BPD-MA) when intravenously injected (5.5 μmol kg(−1)) to C57/BL6 mice bearing a subcutaneously transplanted B1 melanoma gave a maximal accumulation in the tumour within 1–3 h with recoveries of 1.84– 1.96 μmol kg(−1). Irradiation of BPD-MA-load...

Descripción completa

Detalles Bibliográficos
Autores principales: Busetti, A, Soncin, M, Jori, G, Rodgers, M A J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362652/
https://www.ncbi.nlm.nih.gov/pubmed/10070875
http://dx.doi.org/10.1038/sj.bjc.6690131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362652/
https://www.ncbi.nlm.nih.gov/pubmed/10070875
http://dx.doi.org/10.1038/sj.bjc.6690131

Ejemplares similares