Activation of integrin and ceramide signalling pathways can inhibit the mitogenic effect of insulin-like growth factor I (IGF-I) in human breast cancer cell lines

Cell counting, cell cycle analysis and Western immunoblotting were used to examine the effects of non-apoptotic doses of a ceramide analogue, C2, and a synthetic arginine–glycine–aspartic acid (RGD)-containing peptide, RGD, in MCF-7 and T47D cells to determine whether activation of these signalling...

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Detalles Bibliográficos
Autores principales: Perks, C M, Gill, Z P, Newcomb, P V, Holly, J M P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362662/
https://www.ncbi.nlm.nih.gov/pubmed/10070857
http://dx.doi.org/10.1038/sj.bjc.6690113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362662/
https://www.ncbi.nlm.nih.gov/pubmed/10070857
http://dx.doi.org/10.1038/sj.bjc.6690113

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