Cargando…
Activation of integrin and ceramide signalling pathways can inhibit the mitogenic effect of insulin-like growth factor I (IGF-I) in human breast cancer cell lines
Cell counting, cell cycle analysis and Western immunoblotting were used to examine the effects of non-apoptotic doses of a ceramide analogue, C2, and a synthetic arginine–glycine–aspartic acid (RGD)-containing peptide, RGD, in MCF-7 and T47D cells to determine whether activation of these signalling...
Autores principales: | Perks, C M, Gill, Z P, Newcomb, P V, Holly, J M P |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362662/ https://www.ncbi.nlm.nih.gov/pubmed/10070857 http://dx.doi.org/10.1038/sj.bjc.6690113 |
Ejemplares similares
-
The Neglected Insulin: IGF-II, a Metabolic Regulator with Implications for Diabetes, Obesity, and Cancer
por: Holly, Jeff M. P., et al.
Publicado: (2019) -
A prospective study of serum insulin-like growth factor-I (IGF-I), IGF-II, IGF-binding protein-3 and breast cancer risk
por: Allen, N E, et al.
Publicado: (2005) -
Glucose Concentration in Cell Culture Medium Influences the BRCA1-Mediated Regulation of the Lipogenic Action of IGF-I in Breast Cancer Cells
por: Koobotse, Moses O., et al.
Publicado: (2020) -
Actions of IGF-I are differentially regulated by fatty acids in normal and breast cancer epithelial cells
por: Perks, CM, et al.
Publicado: (2008) -
Production of immunoreactive insulin-like growth factor-I (IGF-I) and IGF-I binding proteins by human lung tumours.
por: Reeve, J. G., et al.
Publicado: (1990)