Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas

PTEN is a novel tumour-suppressor gene located on chromosomal band 10q23.3. This region displays frequent loss of heterozygosity (LOH) in a variety of human neoplasms including breast carcinomas. The detection of PTEN mutations in Cowden disease and in breast carcinoma cell lines suggests that PTEN...

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Detalles Bibliográficos
Autores principales: Freihoff, D, Kempe, A, Beste, B, Wappenschmidt, B, Kreyer, E, Hayashi, Y, Meindl, A, Krebs, D, Wiestler, O D, Deimling, A von, Schmutzler, R K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362671/
https://www.ncbi.nlm.nih.gov/pubmed/10070865
http://dx.doi.org/10.1038/sj.bjc.6690121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362671/
https://www.ncbi.nlm.nih.gov/pubmed/10070865
http://dx.doi.org/10.1038/sj.bjc.6690121

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