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Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations
High-dose busulphan-containing chemotherapy regimens have shown high response rates in children with relapsed or refractory neuroblastoma, Ewing's sarcoma and medulloblastoma. However, the anti-tumour activity of busulfan as a single agent remains to be defined, and this was evaluated in athymi...
Autores principales: | Boland, I, Vassal, G, Morizet, J, Terrier-Lacombe, M-J, Valteau-Couanet, D, Kalifa, C, Hartmann, O, Gouyette, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362679/ https://www.ncbi.nlm.nih.gov/pubmed/10070870 http://dx.doi.org/10.1038/sj.bjc.6690126 |
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