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Fractionated administration of irinotecan and cisplatin for treatment of lung cancer: a phase I study
A combination chemotherapy of irinotecan (CPT-11) and cisplatin (CDDP) has been reported to be active for lung cancer. In the previous trial, however, diarrhoea and leucopenia became the major obstacle for sufficient dose escalation of CPT-11 to improve the treatment outcome. We conducted a phase I...
Autores principales: | Ueoka, H, Tabata, M, Kiura, K, Shibayama, T, Gemba, K, Segawa, Y, Chikamori, K, Yonei, T, Hiraki, S, Harada, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362688/ https://www.ncbi.nlm.nih.gov/pubmed/10070901 http://dx.doi.org/10.1038/sj.bjc.6690157 |
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