Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2

For families with a small number of cases of breast and/or ovarian cancer, limited data are available to predict the likelihood of genetic predisposition due to mutations in BRCA1 or BRCA2. In 104 families with three or more affected individuals (average 3.8) seeking counselling at family cancer cli...

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Detalles Bibliográficos
Autores principales: Ligtenberg, M J L, Hogervorst, F B L, Willems, H W, Arts, P J W, Brink, G, Hageman, S, Bosgoed, E A J, Looij, E Van der, Rookus, M A, Devilee, P, Vos, E M A W, Wigbout, G, Struycken, P M, Menko, F H, Rutgers, E J Th, Hoefsloot, E H, Mariman, E C M, Brunner, H G, Veer, L J Van't
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362698/
https://www.ncbi.nlm.nih.gov/pubmed/10188893
http://dx.doi.org/10.1038/sj.bjc.6690235

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