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Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3

Dysregulation of matrix degrading metalloproteinase enzymes (MMPs) leads to increased extracellular matrix turnover, a key event in the local invasion and metastasis of many tumours. The tissue inhibitors of metalloproteinases (TIMPs) limit the activity of MMPs, which suggests their use in gene ther...

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Detalles Bibliográficos
Autores principales:	Baker, A H, George, S J, Zaltsman, A B, Murphy, G, Newby, A C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362728/ https://www.ncbi.nlm.nih.gov/pubmed/10188875 http://dx.doi.org/10.1038/sj.bjc.6690217

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