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Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival

The distal half of chromosome 1p was analysed with 15 polymorphic microsatellite markers in 683 human solid tumours at different locations. Loss of heterozygosity (LOH) was observed at least at one site in 369 cases or 54% of the tumours. LOHs detected ranged from 30–64%, depending on tumour locatio...

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Detalles Bibliográficos
Autores principales: Ragnarsson, G, Eiriksdottir, G, Johannsdottir, J Th, Jonasson, J G, Egilsson, V, Ingvarsson, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362732/
https://www.ncbi.nlm.nih.gov/pubmed/10188892
http://dx.doi.org/10.1038/sj.bjc.6690234