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Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas
Matrix metalloproteinases (MMPs) have been implicated as important factors in gliomas since they may both facilitate invasion into the surrounding brain and participate in neovascularization. We have tested the hypothesis that deregulated expression of gelatinase-A or B, or an activator of gelatinas...
Autores principales: | Forsyth, P A, Wong, H, Laing, T D, Rewcastle, N B, Morris, D G, Muzik, H, Leco, K J, Johnston, R N, Brasher, P M A, Sutherland, G, Edwards, D R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362801/ https://www.ncbi.nlm.nih.gov/pubmed/10206300 http://dx.doi.org/10.1038/sj.bjc.6990291 |
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