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Ca(2+)-induced changes in energy metabolism and viability of melanoma cells

Cancer cells are characterized by a high rate of glycolysis, which is their primary energy source. We show here that a rise in intracellular-free calcium ion (Ca(2+)), induced by Ca(2+)-ionophore A23187, exerted a deleterious effect on glycolysis and viability of B16 melanoma cells. Ca(2+)-ionophore...

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Detalles Bibliográficos
Autores principales: Glass-Marmor, L, Penso, J, Beitner, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362860/
https://www.ncbi.nlm.nih.gov/pubmed/10496345
http://dx.doi.org/10.1038/sj.bjc.6690680