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Involvement of bcl-2 and p21(waf1) proteins in response of human breast cancer cell clones to Tomudex
Mechanisms of resistance to Tomudex include increased thymidylate synthase activity, as well as reduced intracellular drug uptake and polyglutamation. However, little is known about other mechanisms of resistance, such as a possible protection against Tomudex-induced apoptosis mediated by bcl-2. We...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362863/ https://www.ncbi.nlm.nih.gov/pubmed/10496350 http://dx.doi.org/10.1038/sj.bjc.6690685 |