Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast

Five of 43 patients (11.6%) with ductal carcinoma in situ of the breast presented with p53 autoantibodies at diagnosis. Three seropositive patients demonstrated tumour sizes of ≤ 5 mm. There was no association of p53 autoantibody status with age, clinical presentation, histological subtype, tumour s...

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Autores principales: Regele, S, Kohlberger, P, Vogl, F D, Böhm, W, Kreienberg, R, Runnebaum, I B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362899/
https://www.ncbi.nlm.nih.gov/pubmed/10574259
http://dx.doi.org/10.1038/sj.bjc.6690751
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author Regele, S
Kohlberger, P
Vogl, F D
Böhm, W
Kreienberg, R
Runnebaum, I B
author_facet Regele, S
Kohlberger, P
Vogl, F D
Böhm, W
Kreienberg, R
Runnebaum, I B
author_sort Regele, S
collection PubMed
description Five of 43 patients (11.6%) with ductal carcinoma in situ of the breast presented with p53 autoantibodies at diagnosis. Three seropositive patients demonstrated tumour sizes of ≤ 5 mm. There was no association of p53 autoantibody status with age, clinical presentation, histological subtype, tumour size, grading, p53 immunohistochemistry or hormone receptor status. © 1999 Cancer Research Campaign
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spelling pubmed-23628992009-09-10 Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast Regele, S Kohlberger, P Vogl, F D Böhm, W Kreienberg, R Runnebaum, I B Br J Cancer Regular Article Five of 43 patients (11.6%) with ductal carcinoma in situ of the breast presented with p53 autoantibodies at diagnosis. Three seropositive patients demonstrated tumour sizes of ≤ 5 mm. There was no association of p53 autoantibody status with age, clinical presentation, histological subtype, tumour size, grading, p53 immunohistochemistry or hormone receptor status. © 1999 Cancer Research Campaign Nature Publishing Group 1999-10 /pmc/articles/PMC2362899/ /pubmed/10574259 http://dx.doi.org/10.1038/sj.bjc.6690751 Text en Copyright © 1999 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Regele, S
Kohlberger, P
Vogl, F D
Böhm, W
Kreienberg, R
Runnebaum, I B
Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast
title Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast
title_full Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast
title_fullStr Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast
title_full_unstemmed Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast
title_short Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast
title_sort serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362899/
https://www.ncbi.nlm.nih.gov/pubmed/10574259
http://dx.doi.org/10.1038/sj.bjc.6690751
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