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Development of a novel bi-specific monoclonal antibody approach for tumour targeting

To overcome the disadvantages of bi-specific antibody methodologies in vivo, a novel antibody approach has been designed to improve tumour targeting and effector to target ratio. The technique involves biotinylated anti-CD3 Fab fragments and streptavidinylated anti-tumour monoclonal antibodies (mAbs...

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Detalles Bibliográficos
Autores principales:	Koumarianou, A A, Hudson, M, Williams, R, Epenetos, A A, Stamp, G W H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362912/ https://www.ncbi.nlm.nih.gov/pubmed/10507767 http://dx.doi.org/10.1038/sj.bjc.6690712

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