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Altered expression of the suppressors PML and p53 in glioblastoma cells with the antisense-EGF-receptor
Gene amplification and enhanced expression of the epidermal growth factor receptor (EGFR) represent the major molecular genetic alteration in glioblastomas and it may play an essential role in cell growth and in the carcinogenic process. On the other hand, the nuclear suppressor proteins PML and p53...
Autores principales: | Tian, X X, Chan, J Y H, Pang, J C S, Chen, J, He, J H, To, T S S, Leung, S F, Ng, H K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362944/ https://www.ncbi.nlm.nih.gov/pubmed/10576656 http://dx.doi.org/10.1038/sj.bjc.6690798 |
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