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Microsatellite instability and mismatch repair gene inactivation in sporadic pancreatic and colon tumours

Genomic instability has been proposed as a new mechanism of carcinogenesis involved in hereditary non-polyposis colorectal cancer (HNPCC) and in a large number of sporadic cancers like pancreatic and colon tumours. Mutations in human mismatch repair genes have been found in HNPCC patients, but their...

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Detalles Bibliográficos
Autores principales:	Ghimenti, C, Tannergård, P, Wahlberg, S, Liu, T, Giulianotti, P G, Mosca, F, Fornaciari, G, Bevilacqua, G, Lindblom, A, Caligo, M A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363009/ https://www.ncbi.nlm.nih.gov/pubmed/10389971 http://dx.doi.org/10.1038/sj.bjc.6690314

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