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Mutation testing in melanoma families: INK4A, CDK4 and INK4D

The INK4A gene which codes for the cyclin-dependent kinase (CDK) inhibitor INK4A or p16 underlies susceptibility to melanoma in some families. Germline mutations in the gene that codes for the target protein of p16, CDK4, underlie susceptibility in very rare families. We report mutation screening of...

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Detalles Bibliográficos
Autores principales:	Newton Bishop, J A, Harland, M, Bennett, D C, Bataille, V, Goldstein, A M, Tucker, M A, Ponder, B A J, Cuzick, J, Selby, P, Bishop, D T
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363010/ https://www.ncbi.nlm.nih.gov/pubmed/10390011 http://dx.doi.org/10.1038/sj.bjc.6690354

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