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A comparative study of the effects of genistein and 2-methoxyestradiol on the proteolytic balance and tumour cell proliferation

The cytotoxicity of two compounds described as anti-angiogenic, the isoflavone genistein and the oestrogen metabolite 2-methoxyestradiol, has been studied in different human tumour cell lines. Since the degradation of the extracellular matrix is one of the essential steps in angiogenesis, the potent...

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Detalles Bibliográficos
Autores principales: Fajardo, I, Quesada, A R, Castro, I Núñez de, Sánchez-Jiménez, F, Medina, M Á
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363013/
https://www.ncbi.nlm.nih.gov/pubmed/10389972
http://dx.doi.org/10.1038/sj.bjc.6690315