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Enhanced delivery of carboplatin into brain tumours with intravenous Cereport(TM) (RMP-7): dramatic differences and insight gained from dosing parameters
Cereport(TM) (RMP-7) is a selective bradykinin B2 receptor agonist which increases the permeability of the ‘blood–brain tumour barrier’ (BBTB) to increase delivery of chemotherapeutic agents to brain tumours. A series of experiments was performed in an RG2 rodent model of glioma to evaluate and refi...
Autores principales: | Emerich, D F, Snodgrass, P, Dean, R, Agostino, M, Hasler, B, Pink, M, Xiong, H, Kim, B S, Bartus, R T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363031/ https://www.ncbi.nlm.nih.gov/pubmed/10362103 http://dx.doi.org/10.1038/sj.bjc.6690450 |
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