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Synergistic induction of ICAM-1 expression by cisplatin and 5-fluorouracil in a cancer cell line via a NF-κB independent pathway

Cisplatin (CDDP) and 5-fluorouracil (5-FU) are common anti-tumour agents, and the anti-tumour effect of CDDP and 5-FU are synergistically enhanced by combined treatment. To clarify the mechanisms of this synergism, we examined the effect of CDDP and 5-FU on the expression of cell adhesion molecules...

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Detalles Bibliográficos
Autores principales:	Takizawa, K, Kamijo, R, Ito, D, Hatori, M, Sumitani, K, Nagumo, M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363043/ https://www.ncbi.nlm.nih.gov/pubmed/10362102 http://dx.doi.org/10.1038/sj.bjc.6690449

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