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Growth dysregulation and p53 accumulation in human primary colorectal cancer

p53 accumulation is common in colorectal cancer, but effects on growth homeostasis are unclear. In this study, DNA content, cell cycle phase fractions and DNA strand-breaks consistent with apoptosis were assessed by flow cytometry in 42 fresh primary colorectal tumours and matched normal mucosa. p53...

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Detalles Bibliográficos
Autores principales:	Watson, D S, Brotherick, I, Shenton, B K, Wilson, R G, Campbell, F C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363047/ https://www.ncbi.nlm.nih.gov/pubmed/10362117 http://dx.doi.org/10.1038/sj.bjc.6690464

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