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Keratoacanthomas have an immunosuppressive cytokine environment of increased IL-10 and decreased GM-CSF compared to squamous cell carcinomas
To investigate the relationship between keratoacanthoma (KA) and squamous cell carcinoma (SCC), cytokine mRNA in 12 KA and eight SCC were compared. Normal skin was also studied. Reverse transcription polymerase chain reaction (RT-PCR) was used to quantitate mRNA in each sample utilizing DNA standard...
Autores principales: | Lowes, M A, Bishop, G A, Cooke, B E, Barnetson, R StC, Halliday, G M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363088/ https://www.ncbi.nlm.nih.gov/pubmed/10408389 http://dx.doi.org/10.1038/sj.bjc.6690552 |
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